Why You Should Participate in a Chronic Rhinosinusitis Clinical Trial

What is the purpose of clinical research?

Clinical research consists of planned studies that are designed to answer specific questions. These studies are a primary way that researchers can figure out whether a new drug, medical device, diet, or behavioral treatment is safe and effective for the people it is meant to treat.

What is the benefit of a clinical study?

One benefit of a clinical study is that you may receive early access to a new drug, medical device, diet or behavioral treatment. You may learn more about your disease or condition, and work with leading medical professionals to manage it. Another benefit is that you are ultimately making a significant contribution to the advancement of medicine. These advancements will benefit many other people for years to come.

Why should you consider participating in a CRS clinical study?

Deciding to participate in a clinical study is a big deal. Although there are significant benefits, there is a time commitment and there may be other requirements depending on the specific study. Still, clinical studies often provide more advantages than disadvantages. If you’re on the fence about trial participation, consider the following reasons to join:

  • You are interested in learning about CRS
  • You may also be looking to share your story with others and hear about other people’s experience with CRS
  • You have an increased interest in:
    • advancing health within the Black community
    • receiving health information, resources, and research-based medical attention
  • You may have been diagnosed and were told to try different treatments and are unaware of what that means
  • You may have signs and symptoms of CRS like:
    • nasal congestion
    • mucus discharge from the nose or mucus that drips down the back of the throat
    • facial pain, pressure, or “fullness”

To learn more about CRS and clinical research, please click here to join the NOWINCLUDED community.


  1. Coren J. Patient education: Chronic rhinosinusitis (Beyond the Basics). UpToDate. Mar 2023. Accessed Sep 18, 2023.
  2. Rank M. and Holbrook E. Chronic rhinosinusitis without nasal polyposis: Management and prognosis. UpToDate. Sep 2023. Accessed Sep 18, 2023. 
  3. Cho. S, et al. Chronic Rhinosinusitis Without Nasal Polyps. J Allergy Clin Immunol Pract. 2016; 4(4): 575–582.
  4. Mahdavinia M, et al. African American Patients with Chronic Rhinosinusitis Have a Distinct Phenotype of Polyposis Associated with Increased Asthma Hospitalization . J Allergy Clin Immunol Pract. 2016; 4: 658-664.e1.
  5. Soler Z, et al. Chronic rhinosinusitis, race, and ethnicity Am J Rhinol Allergy. 2012; 26(2): 110-6.
  6. Konsur E, et al. Race and ethnicity define disparate clinical outcomes in chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2022; 129(6): 737-741.
  7. Chronic rhinosinusitis without nasal polyps: clinical characteristics and comorbid diseases. American Academy of Allergy, Asthma, & Immunology. Oct 2018. Accessed Sep 18, 2023.
  8. Gosepath J and Pfaar O. Chronic Rhinosinusitis with and without Nasal Polyps. Ento Key – Fastest Otolaryngology & Ophthalmology Insight Engine. Jun 2020. Accessed Sep 18, 2023.

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